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BD-1047 (dihydrobromide)

BD-1047 (dihydrobromide)

Item no.	HY-16996A-10mg
Manufacturer	MedChem Express
CASRN	138356-21-5
Amount	10 mg
Quantity options	10mM/1mL 10 mg 50 mg 5 mg
Category	Food Safety Hormones Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	98.14
Formula	C13H22Br2Cl2N2
Citations	Cell Rep. 2023 Jan 31;42(1):112011.<br>Eur J Pharmacol. 2023 Mar 8;175647.<br>Int Immunopharmacol. 2023 Dec 22:127:111382.<br>Int Immunopharmacol. 2023 Feb 22;117:109907.<br>Mol Med. 2022 Aug 3;28(1):87.<br>Neural Regen Res. 2024 Apr 3.<br>Life Sci. 2020 Sep 15;257:118047.<br>[1]Skuza G, et al. Effect of BD 1047, a sigma1 receptor antagonist, in the animal models predictive of antipsychotic activity. Pharmacol Rep. 2006 Sep-Oct;58(5):626-635.<br>[2]Shimazawa M, et al. Effect of a sigma-1 receptor agonist, cutamesine dihydrochloride (SA4503), on photoreceptor cell death against light-induced damage. Exp Eye Res. 2015 Mar;132:64-72.<br>[3]Rogóz Z, et al. Mechanism of synergistic action following co-treatment with pramipexole and fluoxetine or sertraline in the forced swimming test in rats. Pharmacol Rep. 2006 Jul-Aug;58(4):493-500.
Smiles	CN(C)CCN(CCC1=CC=C(Cl)C(Cl)=C1)C.[H]Br.[H]Br
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	138356-21-5
Available
Product Description	BD-1047 (dihydrobromide) is a selective functional antagonist of sigma-1 receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	437.04
Clinical_Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : 25 mg/mL (ultrasonic)\|H2O : 25 mg/mL (ultrasonic)
Manufacturers Target	Sigma Receptor
Isoform	Sigma 1 Receptor
Pathway	Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-16996A-10mg-safety-datasheet.pdf