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SH-4-54

SH-4-54

Item no.	HY-16975-25mg
Manufacturer	MedChem Express
CASRN	1456632-40-8
Amount	25 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Neural Transcription Factors Targets for Rodent Neurosciences Inhibitors & Compound Libraries Small Molecules By Organ Brain Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.45
Formula	C29H27F5N2O5S
Citations	[1]Haftchenary S, et al. Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma. ACS Med Chem Lett. 2013 Sep 8;4(11):1102-1107.
Smiles	O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(C)S(=O)(C4=C(F)C(F)=C(F)C(F)=C4F)=O)=O)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1456632-40-8
Available
Product Description	SH-4-54 is a STAT inhibitor that binds to STAT3 and STAT5 with KDs of 300, 464 nM, respectively.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	610.59
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	STAT
Manufacturers Target	STAT
Isoform	STAT3; STAT5
Manufacturers Pathway	JAK/STAT Signaling; Stem Cell/Wnt
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-16975-25mg-safety-datasheet.pdf