MC1568

Item no.	HY-16914-50mg
Manufacturer	MedChem Express
CASRN	852475-26-4
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Aging & Neurological Disorders Neural Epigenetics Neural Development Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Bladder Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	97.31
Formula	C17H15FN2O3
Citations	[1]Nebbioso A, et al. Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity ofHDAC-MEF2 complexes. EMBO Rep. 2009 Jul;10(7):776-82.<br/>[2]Venza I, et al. Class II-specific histone deacetylase inhibitors MC1568 and MC1575 suppress IL-8 expression in human melanoma cells. Pigment Cell Melanoma Res. 2013 Mar;26(2):193-204.<br/>[3]Nebbioso A, et al. HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation. J Mol Endocrinol. 2010 Oct;45(4):219-28.<br/>[4]Kassis H, et al. Class IIa histone deacetylases affect neuronal remodeling and functional outcome after stroke. Neurochem Int. 2016 Jun;96:24-31.
Smiles	O=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	852475-26-4
Available
Product Description	MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor, used for cancer research.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	314.31
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 18.5 mg/mL (ultrasonic; warming)
Target	HDAC
Manufacturers Target	HDAC
Isoform	HDAC
Manufacturers Pathway	Cell Cycle/DNA Damage; Epigenetics
Manufacturers Product type	Reference compound

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HY-16914-50mg-safety-datasheet.pdf