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Avoralstat

Avoralstat

Item no.	HY-16735-50mg
Manufacturer	MedChem Express
CASRN	918407-35-9
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 2mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Aygoren-Pursun E, et al. Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat. J Allergy Clin Immunol. 2016 Sep;138(3):934-936.e5.<br/>[2]Cornpropst M, et al. Safety, pharmacokinetics, and pharmacodynamics of avoralstat, an oral plasma kallikrein inhibitor: phase 1 study. Allergy. 2016;71(12):1676-1683.
Smiles	O=C(C1=NC(C(NCC2CC2)=O)=CC=C1C3=CC(OC)=C(C=C)C=C3C(NC4=CC=C(C(N)=N)C=C4)=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BCX4161
Available
Product Description	Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	513.54
Clinical Information	Phase 3
Manufacturers Research Area	Others
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Kallikrein
Manufacturers Target	Kallikrein
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-16735-50mg-safety-datasheet.pdf