Comparison

(8R,9S)-Talazoparib European Partner

Item no. HY-16106A-10mg
Manufacturer MedChem Express
CASRN 1207456-00-5
Amount 10mg
Quantity options 100mg 10mM/1mL 10mg 1 mg 200mg 50mg 5 mg
Category
Type Inhibitors
Clone N/A
Specific against other
Purity 98.36
Citations [1]Wang B, et al. Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-
Smiles O=C1NN=C2C3=C1C=C(F)C=C3N[C@@H](C4=CC=C(F)C=C4)[C@@H]2C5=NC=NN5C
ECLASS 5.1 30220300
ECLASS 6.1 30220300
ECLASS 8.0 32160605
ECLASS 9.0 32160605
ECLASS 10.0.1 32160490
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias (8R,9S)-BMN-673; (8R,9S)-LT-673
Available
Product Description
(8R, 9S)-Talazoparib ((8R, 9S)-BMN-673) is an enantiomer of Talazoparib. (8R, 9S)-Talazoparib is an PARP1 inhibitor, with an IC50 of 144 nM[1].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
380.35
Clinical_Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
DMSO : ≥ 50 mg/mL
Manufacturers Target
PARP
Isoform
PARP1
Pathway
Cell Cycle/DNA Damage; Epigenetics

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10mg
Available: In stock
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