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Ellipticine

Ellipticine

Item no.	HY-15753-10mg
Manufacturer	MedChem Express
CASRN	519-23-3
Amount	10 mg
Quantity options	100mg 10 mg 25 mg 50mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer Heart & Blood Cancer Brain Cancer
Type	Inhibitors
Specific against	other
Purity	98.17
Formula	C17H14N2
Citations	Front Cell Dev Biol. 2019 Sep 20;7:204.<br>J Adv Res. 2023 Jun 6;S2090-1232(23)00148-0.<br>J Cell Biol. 2023 Jan 2;222(1):e202202110.<br>[1]Stiborova M, et al. Molecular mechanisms of antineoplastic action of an anticancer drug ellipticine. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2006 Jul;150(1):13-23.<br>[2]Stiborova M, et al. Ellipticine cytotoxicity to cancer cell lines - a comparative study. Interdiscip Toxicol. 2011 Jun;4(2):98-105.<br>[3]Stiborova M, et al. The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN?) mice and pure enzymes. Int J Mol Sci. 2014 Dec 25;16(1):284-306.
Smiles	CC1=C(C=NC=C2)C2=C(C)C(N3)=C1C4=C3C=CC=C4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NSC 71795
Available
Product Description	Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	246.31
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 5.8 mg/mL (ultrasonic; warming)
Manufacturers Target	Topoisomerase
Isoform	Topo II
Pathway	Cell Cycle/DNA Damage

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