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Tanaproget

Tanaproget

Item no.	HY-15606-10mM
Manufacturer	MedChem Express
CASRN	304853-42-7
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Oncology Food Safety Hormones Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer Uterine, Ovarian & Cervical Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.87
Formula	C16H15N3OS
Citations	[1]Bruner-Tran KL, et al. Down-regulation of endometrial matrix metalloproteinase-3 and -7 expression in vitro and therapeutic regression of experimental endometriosis in vivo by a novel nonsteroidal progesterone receptor agonist, tanaproget. J Clin Endocrinol Metab. 2006 Apr;91(4):1554-60.<br/>[2]Zhang Z, et al. Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget. J Biol Chem. 2005 Aug 5;280(31):28468-75.<br/>[3]Bapst JL, et al. Pharmacokinetics and safety of tanaproget, a nonsteroidal progesterone receptor agonist, in healthy women. Contraception. 2006 Nov;74(5):414-8.
Smiles	N#CC1=CC=C(C2=CC=C(NC(OC3(C)C)=S)C3=C2)N1C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NSP-989
Available
Product Description	Tanaproget (NSP-989) is a novel non-steroidal progesterone receptor agonist.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	297.37
Clinical Information	No Development Reported
Manufacturers Research Area	Endocrinology
Solubility	DMSO : ≥ 50 mg/mL
Target	Progesterone Receptor
Manufacturers Target	Progesterone Receptor
Manufacturers Pathway	Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

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HY-15606-10mM-safety-datasheet.pdf