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Hoechst 33342

Hoechst 33342

Item no.	HY-15559-50mg
Manufacturer	MedChem Express
CASRN	23491-52-3
Amount	50 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 50 mg
Category	Cell Biology Cell Stainings Nuclear Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.94
Formula	C27H28N6O
Citations	[1]Chazotte B. Labeling nuclear DNA with hoechst 33342. Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.prot5557. ACS Appl Mater Interfaces. 2018 Sep 12;10(36):30081-30091. ACS Appl Mater Interfaces. 2024 Aug 20. Acs Biomater Sci Eng. 2023 Apr 11. ACS Nano. 2023 Jul 23. Acta Biomater. 2020 Sep 1;113:289-304. Acta Pharm Sin B. 2024 Feb 10. Aging Cell. 2021 Jul;20(7):e13382. Bioact Mater. 2022 Mar 17;18:91-103. Biochem Biophys Res Commun. 2021 Apr 1;554:206-213. bioRxiv. 2023 May 8. Braz J Med Biol Res. 2021 Jan 15;54(3):e10222. Cell Cycle. 2022 Jan 2;1-16. Cell Death Dis. 2022 Dec 12;13(12):1034. Cell Host Microbe. 2023 Nov 8;31(11):1820-1836.e10. Cell Mol Biol Lett. 2024 Feb 17;29(1):26. Cell Prolif. 2024 May 29:e13678. Cell Rep. 2024 Aug 30;43(9):114652. Cells. 2022 Dec 4;11(23):3923. Chem Eng J. 15 December 2022, 138004. Chem Eng J. 2023 Dec 2, 147850. Chinese Pharmacological Bulletin. 2018 May; 34(5): 620-626. Drug Deliv. 2017 Nov;24(1):1453-1459. Drug Resist Updat. 2024 Jun 14:76:101111. Environ Sci Technol. 2017 Sep 19;51(18):10834-10842. Environ Toxicol Pharmacol. 2024 Feb 15:106:104393. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114919. Exp Ther Med. 2024 July 8. Front Biosci (Landmark Ed). 2022, 27(9), 260. Hum Mol Genet. 2023 May 3;ddad070. J Cell Biol. 2021 Oct 4;220(10):e202011153. J Innate Immun. 2022 Oct 21;1-21. J Lipid Res. 2022 May;63(5):100207. J Obstet Gynaecol Res. 2020 Sep 17;46(12):2561-2572. J Pain Res. 2021 Feb 4;14:297-310. Mar Drugs. 2023 Nov 21, 21(12), 600. Mol Biotechnol. 2023 Dec 1. Nat Commun. 2024 Aug 25;15(1):7319. Neural Regen Res. 2022 Sep;17(9):2029-2035. Neural Regen Res. 2023 Jun;18(6):1339-1346. Oncol Lett. 2023 Nov 16. PeerJ. 2022 Sep 28;10:e14086. Sci Rep. 2023 Dec 18;13(1):22598. Science. 2022 Nov 18;378(6621):eabq7361. Small. 2021 Aug;17(32):e2101368. Stem Cell Res Ther. 2021 Jan 22;12(1):77. Theranostics. 2021 Mar 4;11(10):4655-4671. Cancer Biol Ther. 2018;19(12):1193-1203. Cancer Pathog Ther. 2023 Mar 7. Cell Death Dis. 2024 Mar 8;15(3):200. J Cell Physiol. 2021 Jul;236(7):5278-5292. J Ethnopharmacol. 2022 Jan 29;289:115039. J Ethnopharmacol. 8 October 2021, 114730. J Orthop Translat. 17 October 2022. Radiother Oncol. 2023 Nov 29:110039. Stem Cells Int. 15 Aug 2021.
Smiles	CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(OCC)C=C6)N5)=C4)N3)=C2)CC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	bisBenzimide H 33342, HOE 33342
Shipping condition	Room temperature
Available
Manufacturer - Type	Dye Reagents
Manufacturer - Targets	Autophagy
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	452.55
Product Description	Hoechst 33342 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Manufacturer - Research Area	Others
Solubility	DMSO : 6.25 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : < 0.1 mg/mL
Manufacturer - Pathway	Autophagy
Clinical information	No Development Reported

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