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Hoechst 33342

Hoechst 33342

Item no.	HY-15559-100mg
Manufacturer	MedChem Express
CASRN	23491-52-3
Amount	100 mg
Quantity options	100 mg 10mM*1 mL 10mg 50 mg
Category	Cell Biology Cell Stainings Nuclear Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.94
Formula	C27H28N6O
Citations	ACS Appl Mater Interfaces. 2018 Sep 12;10(36):30081-30091.<br>Acs Biomater Sci Eng. 2023 Apr 11.<br>ACS Nano. 2023 Jul 23.<br>Acta Biomater. 2020 Sep 1;113:289-304.<br>Acta Pharm Sin B. 2024 Feb 10.<br>Aging Cell. 2021 Jul;20(7):e13382.<br>Bioact Mater. 2022 Mar 17;18:91-103.<br>Biochem Biophys Res Commun. 2021 Apr 1;554:206-213.<br>bioRxiv. 2023 May 8.<br>Braz J Med Biol Res. 2021 Jan 15;54(3):e10222.<br>Cell Cycle. 2022 Jan 2;1-16.<br>Cell Death Dis. 2022 Dec 12;13(12):1034.<br>Cell Host Microbe. 2023 Nov 8;31(11):1820-1836.e10.<br>Cell Mol Biol Lett. 2024 Feb 17;29(1):26.<br>Cells. 2022 Dec 4;11(23):3923.<br>Chem Eng J. 15 December 2022, 138004.<br>Chem Eng J. 2023 Dec 2, 147850.<br>Chinese Pharmacological Bulletin. 2018 May; 34(5): 620-626.<br>Drug Deliv. 2017 Nov;24(1):1453-1459. <br>Environ Sci Technol. 2017 Sep 19;51(18):10834-10842.<br>Environ Toxicol Pharmacol. 2024 Feb 15:106:104393.<br>Eur J Med Chem. 2023 Jan 5;245(Pt 2):114919.<br>Front Biosci (Landmark Ed). 2022, 27(9), 260.<br>Hum Mol Genet. 2023 May 3;ddad070.<br>J Cell Biol. 2021 Oct 4;220(10):e202011153.<br>J Innate Immun. 2022 Oct 21;1-21.<br>J Lipid Res. 2022 May;63(5):100207.<br>J Obstet Gynaecol Res. 2020 Sep 17;46(12):2561-2572.<br>J Pain Res. 2021 Feb 4;14:297-310.<br>Mar Drugs. 2023 Nov 21, 21(12), 600.<br>Mol Biotechnol. 2023 Dec 1.<br>Neural Regen Res. 2022 Sep;17(9):2029-2035.<br>Neural Regen Res. 2023 Jun;18(6):1339-1346.<br>Oncol Lett. 2023 Nov 16.<br>PeerJ. 2022 Sep 28;10:e14086.<br>Sci Rep. 2023 Dec 18;13(1):22598.<br>Science. 2022 Nov 18;378(6621):eabq7361.<br>Small. 2021 Aug;17(32):e2101368.<br>Stem Cell Res Ther. 2021 Jan 22;12(1):77.<br>Theranostics. 2021 Mar 4;11(10):4655-4671.<br>Cancer Biol Ther. 2018;19(12):1193-1203. <br>Cancer Pathog Ther. 2023 Mar 7.<br>Cell Death Dis. 2024 Mar 8;15(3):200.<br>J Cell Physiol. 2021 Jul;236(7):5278-5292.<br>J Ethnopharmacol. 2022 Jan 29;289:115039.<br>J Ethnopharmacol. 8 October 2021, 114730.<br>J Orthop Translat. 17 October 2022.<br>Radiother Oncol. 2023 Nov 29:110039.<br>Stem Cells Int. 15 Aug 2021.<br>[1]Chazotte B. Labeling nuclear DNA with hoechst 33342. Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.prot5557.
Smiles	CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(OCC)C=C6)N5)=C4)N3)=C2)CC1
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	bisBenzimide H 33342; HOE 33342
Available
Product Description	Hoechst 33342 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
MolecularWeight	452.55
Clinical_Information	No Development Reported
Manufacturers Research Area	Others
Solubility	DMSO : 6.25 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : < 0.1 mg/mL
Manufacturers Target	Autophagy
Pathway	Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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