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Hoechst 33258

Hoechst 33258

Item no.	HY-15558-50mg
Manufacturer	MedChem Express
CASRN	23491-44-3
Amount	50 mg
Quantity options	100 mg 10mM/1mL 50 mg
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Cell Biology Cell Stainings Nuclear Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.93
Formula	C25H24N6O
Citations	[1]Wang XJ, et al. Newly synthesized bis-benzimidazole derivatives exerting anti-tumor activity through inductionof apoptosis and autophagy. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6297-300.<br>[2]Stolić I, et al. Synthesis, DNA/RNA affinity and antitumour activity of new aromatic diamidines linked by 3,4-ethylenedioxythiophene. Eur J Med Chem. 2011 Feb;46(2):743-55.
Smiles	OC1=CC=C(C2=NC3=CC=C(C4=NC5=CC=C(N6CCN(C)CC6)C=C5N4)C=C3N2)C=C1
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	bisBenzimide H 33258; H 33258
Available
Product Description	Hoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
StorageTemperature	-20°C (Powder, protect from light)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	424.50
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 41.67 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Fluorescent Dye
Pathway	Others

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HY-15558-50mg-safety-datasheet.pdf