« Back
Home /
Hoechst 33258

Hoechst 33258

Item no.	HY-15558-100mg
Manufacturer	MedChem Express
CASRN	23491-44-3
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 50 mg
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Cell Biology Cell Stainings Nuclear Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.93
Formula	C25H24N6O
Citations	[1]Wang XJ, et al. Newly synthesized bis-benzimidazole derivatives exerting anti-tumor activity through inductionof apoptosis and autophagy. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6297-300. [2]Stolić I, et al. Synthesis, DNA/RNA affinity and antitumour activity of new aromatic diamidines linked by 3,4-ethylenedioxythiophene. Eur J Med Chem. 2011 Feb;46(2):743-55.
Smiles	OC1=CC=C(C2=NC3=CC=C(C4=NC5=CC=C(N6CCN(C)CC6)C=C5N4)C=C3N2)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	bisBenzimide H 33258, H 33258
Shipping condition	Cool pack
Available
Manufacturer - Type	Dye Reagents
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Fluorescent Dye
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light)
Molecular Weight	424.50
Product Description	Hoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 41.67 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Others
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-15558-100mg-safety-datasheet.pdf