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GSK269962A

GSK269962A

Item no.	HY-15556-10mM
Manufacturer	MedChem Express
CASRN	850664-21-0
Amount	10mM/1mL
Quantity options	10mM/1mL 10 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.83
Formula	C29H30N8O5
Citations	[1]Doe C, et al. Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities. J Pharmacol Exp Ther. 2007 Jan;320(1):89-98.
Smiles	CCN1C2=CC(OC3=CC=CC(NC(C4=CC=C(OCCN5CCOCC5)C=C4)=O)=C3)=NC=C2N=C1C6=NON=C6N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GSK 269962
Available
Product Description	GSK269962A (GSK 269962) is a potent ROCK inhibitor with IC50s of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively. GSK269962A has anti-inflammatory and vasodilatory activities[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	570.60
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO : 125 mg/mL (ultrasonic)
Target	ROCK
Manufacturers Target	ROCK
Isoform	ROCK1; ROCK2
Manufacturers Pathway	Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Manufacturers Product type	Reference compound

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HY-15556-10mM-safety-datasheet.pdf