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O-Phospho-L-serine

O-Phospho-L-serine

Item no.	HY-15129-10mM
Manufacturer	MedChem Express
CASRN	407-41-0
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 50 mg
Category	Food Safety Allergenes Neuroscience Neural Lineage Markers Neural Transcription Factors Molecular Targets for Neuroscience Neural Signaling Inhibitors & Compound Libraries Small Molecules Amino Acid Analysis
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C3H8NO6P
Citations	[1]Kang HJ, et al. Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors. J Biol Chem. 2015 Jan 30;290(5):2870-8.<br>[2]Kang HJ, et al. Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. J Biol Chem. 2014 Oct 24;289(43):29961-74.<br>[3]Bailey TJ, et al. The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina. Exp Eye Res. 2010 Nov;91(5):601-12.
Smiles	OP(OC[C@@H](C(O)=O)N)(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	L-Serine O-phosphate; L-SOP
Available
Product Description	O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	185.07
Clinical_Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : < 1 mg/mL\|H2O : < 0.1 mg/mL
Manufacturers Target	Endogenous Metabolite; mGluR
Isoform	Human Endogenous Metabolite; mGluR1; mGluR2; mGluR4; mGluR6; mGluR7; mGluR8
Pathway	GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-15129-10mM-safety-datasheet.pdf