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Isotretinoin

Isotretinoin

Item no.	HY-15127-10mM
Manufacturer	MedChem Express
CASRN	4759-48-2
Amount	10mM*1 mL
Quantity options	100 mg 10mM*1 mL 500 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Pancreatic Cancer Brain Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.53
Citations	[1]Layton A. The use of isotretinoin in acne. Dermatoendocrinol. 2009 May;1(3):162-9.<br>[2]Dahl AR, et al. Inhaled isotretinoin (13-cis retinoic acid) is an effective lung cancer chemopreventive agent in A/J mice at low doses: a pilot study. Clin Cancer Res. 2000 Aug;6(8):3015-24<br>[3]Bergoli RD, et al. Isotretinoin effect on alveolar repair after exodontia--a study in rats. Oral Maxillofac Surg. 2011 Jun;15(2):85-92.<br>[4]Ramírez-Flores PN, et al. Isotretinoin and Thalidomide Down-Regulate c-MYC Gene Expression and Modify Proteins Associated with Cancer in Hepatic Cells. Molecules. 2021 Sep 22;26(19):5742.
Smiles	CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C\C(O)=O)=C(C)CCC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	13-cis-Retinoic acid
Available
Product Description	Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity[1][2].
StorageTemperature	-20°C (Powder, protect from light, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	300.44
Clinical_Information	Launched
Manufacturers Research Area	Cancer
Manufacturers Target	Autophagy; Endogenous Metabolite; RAR/RXR
Isoform	Human Endogenous Metabolite
Pathway	Autophagy; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 10mM*1 mL

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