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Cevipabulin fumarate

Cevipabulin fumarate

Item no.	HY-14949C-10mM
Manufacturer	MedChem Express
CASRN	849550-67-0
Amount	10mM/1ML
Quantity options	100 mg 10mM/1ML 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.97
Formula	C22H22ClF5N6O5
Citations	[1]Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68(7):2292-300.<br>[2]Beyer CF, et al. The microtubule-active antitumor compound TTI-237 has both DB01229-like and Leurocristine-like properties. Cancer Chemother Pharmacol. 2009 Sep;64(4):681-9.
Smiles	C[C@@H](C(F)(F)F)NC1=C(C2=C(F)C=C(OCCCNC)C=C2F)C(Cl)=NC3=NC=NN13.O=C(O)/C=C/C(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	TTI-237 fumarate
Available
Product Description	Cevipabulin fumarate (TTI-237 fumarate) is an oral, microtubule-active, antitumor compound and inhibits the binding of [3H]NSC 49842 to tubulin, with an IC50 of 18-40 nM for cytotoxicity in human tumor cell line[1][2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	580.89
Clinical_Information	Phase 1
Manufacturers Research Area	Cancer
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 1.43 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Microtubule/Tubulin
Pathway	Cell Cycle/DNA Damage; Cytoskeleton

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-14949C-10mM-safety-datasheet.pdf