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Afegostat (D-Tartrate)

Afegostat (D-Tartrate)

Item no.	HY-14829E-25mg
Manufacturer	MedChem Express
CASRN	957230-65-8
Amount	25 mg
Quantity options	10mg 1 mg 25 mg 50mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Richter F, et al. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct;11(4):840-56.
Smiles	OC[C@@H]1[C@H]([C@@H](CNC1)O)O.OC([C@@H](O)[C@H](O)C(O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	D-Isofagomine (D-Tartrate); Isofagomine (D-Tartrate)
Available
Product Description	Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity[1].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture and light)
Shipping	Blue Ice
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	297.26
Clinical_Information	Phase 2
Manufacturers Research Area	Neurological Disease
Solubility	H2O : ≥ 50 mg/mL
Manufacturers Target	Glucosidase
Pathway	Metabolic Enzyme/Protease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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