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L-Glutamic acid

L-Glutamic acid

Item no.	HY-14608-10mM
Manufacturer	MedChem Express
CASRN	56-86-0
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 1 g 500 mg 5 g
Category	Food Safety Inhibitors & Compound Libraries Small Molecules Amino Acid Analysis
Type	Inhibitors
Specific against	other
Purity	99.84
Citations	J Transl Med. 2024 Feb 18;22(1):178.<br>Neurochem Int. 2023 Jul 24;105587.<br>Redox Biol. 2024 Mar 4:71:103112.<br>Res Sq. 2024 May 20.<br>[1] Liberatore F, et al. Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration. Neuroscience. 2017 Nov 5;363:142-149.<br>[2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.<br>[3]Boga Pekmezekmek A, et al. L-Glutamic acid monosodium salt reduces the harmful effect of lithium on the development of Xenopus laevis embryos. Environ Sci Pollut Res Int. 2020 Nov;27(33):42124-42132.<br>[4]Croce N, et al. Hydrochloric acid alters the effect of L-glutamic acid on cell viability in human neuroblastoma cell cultures. J Neurosci Methods. 2013 Jul 15;217(1-2):26-30.<br>[5]Salyha N, et al. Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats. Environ Toxicol Pharmacol. 2018 Dec;64:155-163.
Smiles	OC(CC[C@H](N)C(O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	56-86-0
Available
Product Description	L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases[1][2][3][4][5].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	147.13
Clinical_Information	Launched
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : 6.25 mg/mL (ultrasonic)
Manufacturers Target	Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
Isoform	AMPA Receptor; Human Endogenous Metabolite; Microbial Metabolite
Pathway	Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-14608-10mM-safety-datasheet.pdf