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L-Glutamic acid

L-Glutamic acid

Item no.	HY-14608-100mg
Manufacturer	MedChem Express
CASRN	56-86-0
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg 5 g
Category	Food Safety Inhibitors & Compound Libraries Small Molecules Amino Acid Analysis
Type	Inhibitors
Specific against	other
Purity	99.84
Citations	[1] Liberatore F, et al. Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration. Neuroscience. 2017 Nov 5;363:142-149. [2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7. [3]Boga Pekmezekmek A, et al. L-Glutamic acid monosodium salt reduces the harmful effect of lithium on the development of Xenopus laevis embryos. Environ Sci Pollut Res Int. 2020 Nov;27(33):42124-42132. [4]Croce N, et al. Hydrochloric acid alters the effect of L-glutamic acid on cell viability in human neuroblastoma cell cultures. J Neurosci Methods. 2013 Jul 15;217(1-2):26-30. [5]Salyha N, et al. Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats. Environ Toxicol Pharmacol. 2018 Dec;64:155-163. Amino Acids. 2024 Sep 18;56(1):56. J Transl Med. 2024 Feb 18;22(1):178. Neurochem Int. 2023 Jul 24;105587. Redox Biol. 2024 Mar 4:71:103112. Res Sq. 2024 Jun 03. Res Sq. 2024 May 20.
Smiles	OC(CC[C@H](N)C(O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	56-86-0
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
Shipping Temperature	Room Temperature
Storage Conditions	Store at room temperature 3 years
Molecular Weight	147.13
Product Description	L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases[1][2][3][4][5].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : 6.25 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Isoform	AMPA Receptor; Human Endogenous Metabolite; Microbial Metabolite
Clinical information	Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-14608-100mg-safety-datasheet.pdf