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Fosaprepitant (dimeglumine)

Fosaprepitant (dimeglumine)

Item no.	HY-14407A-5mg
Manufacturer	MedChem Express
CASRN	265121-04-8
Amount	5 mg
Quantity options	100 mg 10mM*1 mL 10 mg 50 mg 5 mg
Category	Food Safety Drugs Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.0
Formula	C37H56F7N6O16P
Citations	New J Chem. 29th November 2021.<br>Cancer Biol Ther. 2019;20(5):653-665.<br>[1]Pranav Prasoon, et al. Role of fosaprepitant, a neurokinin Type 1 receptor antagonist, in morphine-induced antinociception in rats. Indian J Pharmacol. 2016 Jul-Aug; 48(4): 394-398.
Smiles	O=C1N=C(CN2[C@@H](C3=CC=C(F)C=C3)[C@@H](O[C@H](C)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)OCC2)NN1P(O)(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MK-0517; L785298
Available
Product Description	Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV)[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	1004.83
Clinical_Information	Launched
Manufacturers Research Area	Neurological Disease; Endocrinology; Cancer
Solubility	10 mM in DMSO\|H2O : 50 mg/mL (ultrasonic)
Manufacturers Target	Neurokinin Receptor
Pathway	GPCR/G Protein; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-14407A-5mg-safety-datasheet.pdf