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Finafloxacin

Finafloxacin

Item no.	HY-13451-10mg
Manufacturer	MedChem Express
CASRN	209342-40-5
Amount	10 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 50 mg 5 mg
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.87
Formula	C20H19FN4O4
Citations	[1]McKeage K. Finafloxacin: first global approval. Drugs. 2015 Apr;75(6):687-93.
Smiles	O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4C[C@]5([H])OCCN[C@@]5([H])C4)=C3C#N)C1=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	209342-40-5
Available
Product Description	Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. Target: Antibacterial Finafloxacin is a pH-activated fluoroquinolone (belonging to a new 8-cyano subclass) to treat serious bacterial infections associated with an acidic environment, including urinary tract infections (UTIs) and Helicobacter pylori infections. Finafloxacin exhibits optimal efficacy in slightly acidic environments (pH 5.0-6.0), under which other fluoroquinolones lose activity. Finafloxacin is highly selective for bacterial type II topoisomerases, including DNA gyrase and DNA topoisomerase IV. [1]
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	398.39
Clinical Information	Launched
Manufacturers Research Area	Infection
Solubility	DMSO : 6.4 mg/mL (ultrasonic; warming)
Target	Antibiotic; Bacterial
Manufacturers Target	Antibiotic; Bacterial
Isoform	Quinolone
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Reference compound

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HY-13451-10mg-safety-datasheet.pdf