Comparison

Dorsomorphin (dihydrochloride) European Partner

Item no. HY-13418-5mg
Manufacturer MedChem Express
CASRN 1219168-18-9
Amount 5 mg
Quantity options 100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category
Type Inhibitors
Clone N/A
Specific against other
Purity 99.91
Formula C24H27Cl2N5O
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Smiles [H]Cl.[H]Cl.C12=C(C3=CC=NC=C3)C=NN1C=C(C4=CC=C(OCCN5CCCCC5)C=C4)C=N2
ECLASS 5.1 30220300
ECLASS 6.1 30220300
ECLASS 8.0 32160605
ECLASS 9.0 32160605
ECLASS 10.0.1 32160490
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Compound C (dihydrochloride); BML-275 (dihydrochloride)
Available
Product Description
Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599).
StorageTemperature
4°C (Powder, sealed storage, away from moisture)
Shipping
Room Temperature
Manufacturers Applications
Cancer-Kinase/protease
MolecularWeight
472.41
Clinical_Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
DMSO : 5 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Manufacturers Target
AMPK; Autophagy; Organoid; TGF-β Receptor
Isoform
ALK2; ALK3; ALK6; AMPK
Pathway
Autophagy; Epigenetics; PI3K/Akt/mTOR; Stem Cell/Wnt; TGF-beta/Smad

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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