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SMND-309

SMND-309

Item no.	HY-13056-5mg
Manufacturer	MedChem Express
CASRN	1065559-56-9
Amount	5 mg
Quantity options	10mM/1mL 10 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Specific against	other
Purity	96.81
Formula	C18H14O8
Citations	[1]Hou J, Tian J, Jiang W, Gao Y, Fu F. Therapeutic effects of SMND-309, a new metabolite of salvianolic acid B, on experimental liver fibrosis. Eur J Pharmacol. 2011 Jan 10;650(1):390-5. [2]Yang J, Zhang G, Tian J, Li C, Jiang W, Xing Y, Zhu H, Hou J, Xu H, Wu J. Cardioprotective effect of SMND-309, a novel derivate of salvianolic acid B on acute myocardial infarction in rats. Basic Clin Pharmacol Toxicol. 2010 Apr;106(4):317-23. [3]Wang Y, Zhang J, Han M, et al. SMND-309 promotes neuron survival through the activation of the PI3K/Akt/CREB-signalling pathway. Pharm Biol. 2016;54(10):1982-1990.
Smiles	OC1=C(C(/C=C/C(O)=O)=CC=C1O)/C(C(O)=O)=C\C2=CC(O)=C(C=C2)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1065559-56-9
Available
Product Description	SMND-309 is a metabolite of salvianolic acid B, and exhibits neuroprotective effects in cultured neurons and in permanent middle cerebral artery occlusion rats[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	358.30
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : ≥ 3.7 mg/mL
Target	Drug Metabolite
Manufacturers Target	Drug Metabolite
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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HY-13056-5mg-safety-datasheet.pdf