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MCL-1/BCL-2-IN-2

MCL-1/BCL-2-IN-2

Item no.	HY-129700-10mg
Manufacturer	MedChem Express
CASRN	2163793-44-8
Amount	10 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Oncology By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Cell Biology Cell Status Apoptosis Autophagy Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Testicular & Prostate Cancer
Type	Inhibitors
Specific against	other
Purity	99.12
Formula	C20H15BrN2O2S
Citations	[1]Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
Smiles	O=C1N(CCN)C(C2=CC=C(SC3=CC=C(Br)C=C3)C4=CC=CC1=C24)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2163793-44-8
Available
Product Description	MCL-1/BCL-2-IN-2 (Compound 6) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	427.31
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Bcl-2 Family
Manufacturers Target	Bcl-2 Family
Manufacturers Pathway	Apoptosis
Manufacturers Product type	Reference compound

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HY-129700-10mg-safety-datasheet.pdf