ITD-1

Item no.	HY-12704-100mg
Manufacturer	MedChem Express
CASRN	1099644-42-4
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer
Type	Inhibitors
Specific against	other
Purity	99.83
Formula	C27H29NO3
Citations	[1]Willems E, et al. Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012 Aug 3;11(2):242-52.
Smiles	O=C(C1=C(C)NC2=C(C(CC(C)(C)C2)=O)C1C3=CC=C(C4=CC=CC=C4)C=C3)OCC
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1099644-42-4
Available
Product Description	ITD-1 is the first selective TGFβ receptor inhibitor with an IC50 of 460 nM.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	415.52
Clinical_Information	No Development Reported
Manufacturers Research Area	Cardiovascular Disease
Solubility	DMSO : 28 mg/mL (ultrasonic; warming)
Manufacturers Target	TGF-β Receptor
Pathway	TGF-beta/Smad

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HY-12704-100mg-safety-datasheet.pdf