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MPI-0479605

MPI-0479605

Item no.	HY-12660-10mg
Manufacturer	MedChem Express
CASRN	1246529-32-7
Amount	10 mg
Quantity options	100 mg 10mM/1mL 10 mg 2 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer
Type	Inhibitors
Specific against	other
Purity	99.51
Formula	C22H29N7O
Citations	[1]Tardif KD, et al. Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1. Mol Cancer Ther. 2011 Dec;10(12):2267-2275.
Smiles	CC(C=C(N1CCOCC1)C=C2)=C2NC3=NC4=C(N=CN4)C(NC5CCCCC5)=N3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1246529-32-7
Available
Product Description	MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC50 of 1.8 nM.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	407.51
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 11 mg/mL (ultrasonic; warming)
Manufacturers Target	Apoptosis; Mps1
Pathway	Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-12660-10mg-safety-datasheet.pdf