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3,5-Diiodothyropropionic acid

3,5-Diiodothyropropionic acid

Item no.	HY-126236-10mM
Manufacturer	MedChem Express
CASRN	1158-10-7
Amount	10 mM/1 mL
Quantity options	10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Food Safety Inhibitors & Compound Libraries Small Molecules Food Additives Preservatives
Type	Inhibitors
Specific against	other
Purity	99.20
Formula	C15H12I2O4
Citations	[1]Pennock GD, et al. Cardiac effects of 3,5-diiodothyropropionic acid, a thyroid hormone analog with inotropic selectivity. J Pharmacol Exp Ther. 1992 Oct;263(1):163-9.
Smiles	O=C(O)CCC1=CC(I)=C(OC2=CC=C(O)C=C2)C(I)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Thyroid Hormone Receptor
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	510.06
Product Description	3, 5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively[1].
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Vitamin D Related/Nuclear Receptor
Clinical information	Phase 2

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HY-126236-10mM-safety-datasheet.pdf