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Gly-β-MCA

Gly-β-MCA

Item no.	HY-114392-10mM
Manufacturer	MedChem Express
CASRN	66225-78-3
Amount	10mM/1mL
Quantity options	10mM/1mL 10 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.74
Formula	C26H43NO6
Citations	[1]Jiang C, et al. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nat Commun. 2015 Dec 15;6:10166.
Smiles	C[C@@H]([C@@]1([H])CC[C@@]2([H])[C@@]3([H])[C@]([C@]4(CC[C@@H](O)C[C@H]4[C@H](O)[C@@H]3O)C)([H])CC[C@]12C)CCC(NCC(O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	66225-78-3
Available
Product Description	Gly-β-MCA, a bile acid, is a potent, sable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor that may be a candidate for the treatment of metabolic disorders[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	465.62
Clinical Information	No Development Reported
Manufacturers Research Area	Metabolic Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL (ultrasonic)
Target	Autophagy; FXR
Manufacturers Target	Autophagy; FXR
Manufacturers Pathway	Autophagy; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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HY-114392-10mM-safety-datasheet.pdf