Comparison

USL311 European Partner

Item no. HY-114244-10mg
Manufacturer MedChem Express
CASRN 1373268-67-7
Amount 10 mg
Quantity options 100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.97
Formula C24H34N6O
Citations [1]Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1<br/>[2]Takacs GP, et al. Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy. Pharmacol Ther. 2021 Jun;222:107790.
Smiles O=C(C1=NC(N2CCN(C3CCN(C(C)C)CC3)CCC2)=CC=C1)NC4=CC=NC=C4
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 1373268-67-7
Available
Product Description
USL311 is a potent and selective CXCR4 antagonist, with anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4[1].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
422.57
Clinical Information
Phase 2
Manufacturers Research Area
Cancer; Endocrinology
Solubility
DMSO : 18.57 mg/mL (ultrasonic; warming; heat to 80°C)
Target
CXCR
Manufacturers Target
CXCR
Isoform
CXCR4
Manufacturers Pathway
GPCR/G Protein; Immunology/Inflammation
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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