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RR-11a analog

RR-11a analog

Item no.	HY-112205A-5mg
Manufacturer	MedChem Express
CASRN	685543-66-2
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.12
Formula	C22H29N5O8
Citations	[1]Götz MG, et al. Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens. J Med Chem. 2008 May 8;51(9):2816-32.<br/>[2]Ekici OD, et al. Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases. J Med Chem. 2004 Apr 8;47(8):1889-92.
Smiles	O=C(N[C@@H](C)C(N[C@@H](C)C(NN(CC(N)=O)C(/C=C/C(OCC)=O)=O)=O)=O)OCC1=CC=CC=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	685543-66-2
Available
Product Description	RR-11a analog is a potent and irreversible inhibitor of Schistosoma mansoni legumain, with an IC50 of 31 nM. RR-11a analog is an aza-Asn derivative and aza-peptide Michael acceptor[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	491.49
Clinical Information	No Development Reported
Manufacturers Research Area	Infection
Solubility	DMSO : 125 mg/mL (ultrasonic)\|H2O : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Legumain; Parasite
Manufacturers Target	Legumain; Parasite
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Reference compound

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HY-112205A-5mg-safety-datasheet.pdf