Comparison

dTRIM24 European Partner

Item no. HY-111519-5mg
Manufacturer MedChem Express
CASRN 2170695-14-2
Amount 5 mg
Quantity options 100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.92
Formula C55H68N8O13S2
Citations [1]Gechijian LN, et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nat Chem Biol. 2018 Apr;14(4):405-412.
Smiles CN(C1=C2C=C(C(NS(C3=CC(C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@H](C4)O)C(NCC5=CC=C(C=C5)C6=C(N=CS6)C)=O)=O)=O)=O)=CC=C3)(=O)=O)=C1)OC7=CC=CC(OCCC)=C7)C(N2C)=O
ECLASS 5.1 30220300
ECLASS 6.1 30220300
ECLASS 8.0 32160605
ECLASS 9.0 32160605
ECLASS 10.0.1 32160490
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 2170695-14-2
Available
Product Description
dTRIM24 is a selective bifunctional degrader of TRIM24 based on PROTAC, consists of ligands for von Hippel-Lindau and TRIM24.
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
1113.30
Clinical_Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
DMSO : 100 mg/mL (ultrasonic)|Methanol : 150 mg/mL (ultrasonic)
Manufacturers Target
Epigenetic Reader Domain; PROTACs
Pathway
Epigenetics; PROTAC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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