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BAY-218

BAY-218

Item no.	HY-111449-100mg
Manufacturer	MedChem Express
CASRN	2162982-11-6
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.95
Formula	C20H17ClFN3O3
Citations	[1]Norbert Schmees, et al. 3-oxo-2,6-diphenyl-2,3-dihydropyridazine-4-carboxamides. WO2017202816A1.
Smiles	O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CC=CC(F)=C3)C1=O)N[C@@H](C)CO
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AHR antagonist 1
Similar products	2162982-11-6
Available
Product Description	BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	401.82
Clinical Information	Phase 1
Manufacturers Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO : ≥ 250 mg/mL
Target	Aryl Hydrocarbon Receptor
Manufacturers Target	Aryl Hydrocarbon Receptor
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-111449-100mg-safety-datasheet.pdf