Item no. |
HY-11018-100mg |
Manufacturer |
MedChem Express
|
CASRN |
106266-06-2 |
Amount |
100 mg |
Quantity options |
100 mg
10mM/1mL
10 mg
500 mg
50 mg
5 mg
|
Category |
|
Type |
Inhibitors |
Clone |
N/A |
Specific against |
other |
Purity |
99.92 |
Formula |
C23H27FN4O2 |
Citations |
[1]Nyberg S, et al. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology (Berl). 1993;110(3):265-72.<br/>[2]Zhu HJ, et al. Risperidone and paliperidone inhibit p-glycoprotein activity in vitro. Neuropsychopharmacology. 2007 Apr;32(4):757-64.<br/>[3]Chen ML, et al. Risperidone modulates the cytokine and chemokine release of dendritic cells and induces TNF-α-directed cell apoptosis in neutrophils. Int Immunopharmacol. 2012 Jan;12(1):197-204.<br/>[4]Bardgett ME, et al. Adult rats treated with risperidone during development are hyperactive. Exp Clin Psychopharmacol. 2013 Jun;21(3):259-67. |
Smiles |
O=C1C(CCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)=C(C)N=C5N1CCCC5 |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
R 64 766 |
Available |
|
Product Description |
Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively. |
StorageTemperature |
-20°C, 3 years; 4°C, 2 years (Powder) |
Shipping |
Room Temperature |
Manufacturers Applications |
Neuroscience-Neuromodulation |
MolecularWeight |
410.48 |
Clinical Information |
Launched |
Manufacturers Research Area |
Neurological Disease |
Solubility |
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C) |
Target |
5-HT Receptor; Dopamine Receptor; P-glycoprotein |
Manufacturers Target |
5-HT Receptor; Dopamine Receptor; P-glycoprotein |
Isoform |
5-HT2 Receptor; D2 Receptor |
Manufacturers Pathway |
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling |
Manufacturers Product type |
Reference compound |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.