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N33-TEG-COOH

N33-TEG-COOH

Item no.	HY-108370-10mM
Manufacturer	MedChem Express
CASRN	201467-81-4
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 1 g 250 mg 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.08
Formula	C10H19N3O6
Citations	[1]Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.
Smiles	O=C(O)COCCOCCOCCOCCN=[N+]=[N-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	N3-TEG-COOH; 14-Azido-3,6,9,12-tetraoxatetradecanoic acid
Available
Product Description	N33-TEG-COOH (N3-TEG-COOH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. N33-TEG-COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	277.27
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)\|Ethanol : 100 mg/mL (ultrasonic)
Target	PROTAC Linkers
Manufacturers Target	PROTAC Linkers
Isoform	PEG Linkers
Manufacturers Pathway	PROTAC
Manufacturers Product type	Reference compound

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HY-108370-10mM-safety-datasheet.pdf