Comparison

Pridopidine European Partner

Item no. HY-10684-5mg
Manufacturer MedChem Express
CASRN 346688-38-8
Amount 5 mg
Quantity options 100 mg 10mM/1mL 10 mg 25 mg 2 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.85
Formula C15H23NO2S
Citations [1]Geva M, et al. Pridopidine activates neuroprotective pathways impaired in Huntington Disease. Hum Mol Genet. 2016 Sep 15;25(18):3975-3987.<br>[2]Squitieri F, et al. Pridopidine, a dopamine stabilizer, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse J Cell Mol Med. 2015 Nov;19(11):2540-8. model.
Smiles O=S(C1=CC(C2CCN(CCC)CC2)=CC=C1)(C)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias ACR16; ASP2314; FR310826
Available
Product Description
Pridopidine, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with Ki between 70 and 80 nM, which is ~100× higher than its affinity toward D2R.
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Neuroscience-Neurodegeneration
MolecularWeight
281.41
Clinical_Information
Phase 3
Manufacturers Research Area
Neurological Disease
Solubility
DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target
Dopamine Receptor
Isoform
D2 Receptor
Pathway
GPCR/G Protein; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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