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S 38093

S 38093

Item no.	HY-104003-10mM
Manufacturer	MedChem Express
CASRN	862896-30-8
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 50 mg 5 mg
Category	Oncology Food Safety Histamines Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Neuronal Cell Markers Stem Cell Markers
Type	Inhibitors
Specific against	other
Purity	99.86
Formula	C17H24N2O2
Citations	[1]Guilloux JP, et al. S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. Sci Rep. 2017 Feb 20;7:42946. [2]Sors A, et al. Mechanistic characterization of S 38093, a novel inverse agonist at histamine H3 receptors. Eur J Pharmacol. 2017 May 15;803:11-23
Smiles	O=C(N)C1=CC=C(OCCCN2CC3C(CCC3)C2)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	862896-30-8
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Histamine Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	288.38
Product Description	S 38093 is a brain-penetrant, orally active antagonist of H3 receptor, with Kis of 8.8, 1.44 and 1.2 μM for rat, mouse and human H3 receptors, respectively.
Manufacturer - Research Area	Neurological Disease; Endocrinology
Solubility	DMSO : 2 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Isoform	H3 Receptor
Clinical information	No Development Reported

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HY-104003-10mM-safety-datasheet.pdf