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(S,R,S)-AHPC-PEG2-NH2 (hydrochloride)

(S,R,S)-AHPC-PEG2-NH2 (hydrochloride)

Item no.	HY-103603-100mg
Manufacturer	MedChem Express
CASRN	2097973-72-1
Amount	100 mg
Quantity options	100 mg 10 mg 1 g 25 mg 2g 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.77
Formula	C28H42ClN5O6S
Citations	[1]Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.
Smiles	O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	VH032-PEG2-NH2 (hydrochloride); VHL Ligand-Linker Conjugates 3 (hydrochloride); E3 ligase Ligand-Linker Conjugates 6
Available
Product Description	(S, R, S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S, R, S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	612.18
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 150 mg/mL (ultrasonic)\|H2O : 100 mg/mL (ultrasonic)
Manufacturers Target	E3 Ligase Ligand-Linker Conjugates
Isoform	von Hippel-Lindau (VHL)
Pathway	PROTAC

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HY-103603-100mg-safety-datasheet.pdf