FIN56

Item no.	HY-103087-100mg
Manufacturer	MedChem Express
CASRN	1083162-61-1
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.27
Formula	C25H31N3O5S2
Citations	[1]Kenichi Shimada, et al. Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nat Chem Biol. 2016 Jul;12(7):497-503.<br/>[2]Michael M Gaschler, et al. FINO<sub>2</sub> initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol. 2018 May;14(5):507-515.<br/>[3]Yangchun Xie, et al. The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity. Cell Rep. 2017 Aug 15;20(7):1692-1704.
Smiles	O=S(C1=CC(/C2=N\O)=C(C3=C2C=C(S(=O)(NC4CCCCC4)=O)C=C3)C=C1)(NC5CCCCC5)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1083162-61-1
Available
Product Description	FIN56 is a specific inducer of ferroptosis. FIN56 induces ferroptosis by inducing degradation of GPX4. FIN56 also binds to and activates squalene synthase[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	517.66
Clinical Information	No Development Reported
Manufacturers Research Area	Others
Solubility	DMSO : ≥ 100 mg/mL
Target	Ferroptosis
Manufacturers Target	Ferroptosis
Manufacturers Pathway	Apoptosis
Manufacturers Product type	Reference compound

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HY-103087-100mg-safety-datasheet.pdf