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Saxagliptin (hydrate)

Saxagliptin (hydrate)

Item no.	HY-10285A-100mg
Manufacturer	MedChem Express
CASRN	945667-22-1
Amount	100 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.0
Citations	[1]Chun-Jun Li, et al. Saxagliptin Induces β-Cell Proliferation through Increasing Stromal Cell-Derived Factor-1α In Vivo and In Vitro. Front Endocrinol (Lausanne). 2017 Nov 27;8:326.<br/>[2]Darshan J Dave. Saxagliptin: A dipeptidyl peptidase-4 inhibitor in the treatment of type 2 diabetes mellitus. J Pharmacol Pharmacother. 2011 Oct;2(4):230-5.<br/>[3]Carolyn F Deacon, et al. Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. Adv Ther. 2009 May;26(5):488-99.
Smiles	N[C@@H]([C@](C[C@H](C1)C2)(C[C@@H]1C3)C[C@]23O)C(N([C@@H](C4)C#N)[C@@H]5[C@H]4C5)=O.O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BMS-477118 (hydrate)
Available
Product Description	Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research[1][2][3].
StorageTemperature	-20°C (Powder, protect from light, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	333.43
Clinical Information	Launched
Manufacturers Research Area	Metabolic Disease
Solubility	10 mM in DMSO
Target	Dipeptidyl Peptidase
Manufacturers Target	Dipeptidyl Peptidase
Isoform	DPP-4
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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