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Edoxaban

Edoxaban

Item no.	HY-10264-50mg
Manufacturer	MedChem Express
CASRN	480449-70-5
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.62
Formula	C24H30ClN7O4S
Citations	Authorea. 2023 Apr 17.<br>Elife. 2022 Mar 23:11:e77444.<br>Molecules. 2023 Feb 28.<br>Thromb Res. 2021 Jan;197:141-143.<br>Virology. 2023 Jun 21.<br>PLoS One. 2024 May 15;19(5):e0292628.<br>[1]Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9.
Smiles	O=C(N(C)C)[C@@H](CC1)C[C@H]([C@H]1NC(C(NC(C=C2)=NC=C2Cl)=O)=O)NC(C3=NC(CC4)=C(CN4C)S3)=O
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	DU-176
Available
Product Description	Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban exhibits more than 10, 000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	548.06
Clinical_Information	Launched
Manufacturers Research Area	Cardiovascular Disease; Cancer
Solubility	DMSO : 10 mg/mL (ultrasonic)
Manufacturers Target	Factor Xa; Thrombin
Pathway	Metabolic Enzyme/Protease

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-10264-50mg-safety-datasheet.pdf