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Gamitrinib TPP

Gamitrinib TPP

Item no.	HY-102007-1mg
Manufacturer	MedChem Express
CASRN	1131626-46-4
Amount	1mg
Quantity options	100 mg 1 ea 1mg 5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	Exp Ther Med. September 2, 2021.<br/>bioRxiv. 2024 Jan 2.<br/>Cancer Lett. 2022 Sep 13;215915.<br/>Clin Cancer Res. 2022 Mar 4;clincanres.0833.2021.<br/>Elife. 2021 Jun 16;10:e63104.<br/>Front Biosci (Landmark Ed). 2023 Sep 26, 28(9), 227.<br/>Nature. 2020 Mar;579(7799):433-437. <br/>Research Square Preprint. 2020 Sep.<br/>SSRN. 2023 Jul 11.<br/>[1]Markus D. Siegelin, et al. Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells. J Clin Invest. 2011 Apr 1; 121(4): 1349–1360.
Smiles	O=C(C=C1NC(/C(C)=C/C=C/[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@H]2O)=O)C(NCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=C(C[C@H](C[C@@H]2OC)C)C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1131626-46-4
Available
Product Description	Gamitrinib TPP is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	891.06
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	HSP
Manufacturers Target	HSP
Isoform	HSP90
Manufacturers Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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