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Ilaprazole

Ilaprazole

Item no.	HY-101664-50mg
Manufacturer	MedChem Express
CASRN	172152-36-2
Amount	50 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 2 mg 50 mg 5 mg
Category	Food Safety Histamines Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.97
Formula	C19H18N4O2S
Citations	[1]Kwon D, et al. Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo. Arzneimittelforschung. 2001;51(3):204-13. [2]Zheng M, et al. Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase. Oncotarget. 2017;8(24):39143-39153.
Smiles	O=S(C1=NC2=CC=C(N3C=CC=C3)C=C2N1)CC4=NC=CC(OC)=C4C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	IY-81149
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Proton Pump; TOPK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	366.44
Product Description	Ilaprazole (IY-81149) is an orally active proton pump inhibitor. Ilaprazole irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of pump inhibitory activity of 6 μM in rabbit parietal cell preparation. Ilaprazole is used for the research of gastric ulcers. Ilaprazole is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor[1][2].
Manufacturer - Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO : ≥ 35 mg/mL\|Ethanol : 5 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel
Clinical information	Launched

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HY-101664-50mg-safety-datasheet.pdf