Item no. |
HY-101410-10mg |
Manufacturer |
MedChem Express
|
CASRN |
30344-00-4 |
Amount |
10 mg |
Quantity options |
100 mg
10 mM/1 mL
10 mg
25 mg
50 mg
5 mg
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
98.0 |
Formula |
C8H18N4O2 |
Citations |
[1]Bode-Böger SM,et al. Symmetrical dimethylarginine: a new combined parameter for renal function and extent ofcoronary artery disease. [2]Schepers E, et al. Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.Clin J Am Soc Nephrol. 2011 Oct;6(10):2374-83. [3]Nabity MB, et al. Symmetric Dimethylarginine Assay Validation, Stability, and Evaluation as a Marker for the EarlyDetection of Chronic Kidney Disease in Dogs. J Vet Intern Med. 2015 Jul-Aug;29(4):1036-44. [4]Veldink H, et al. Effects of chronic SDMA infusion on glomerular filtration rate, blood pressure, myocardial function and renal histology in C57BL6/J mice. Nephrol Dial Transplant. 2013 Jun;28(6):1434-9. |
Smiles |
N[C@@H](CCC/N=C(NC)/NC)C(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
Symmetric dimethylarginine, NG,NG'-Dimethyl-L-arginine |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Type |
Natural Products |
Manufacturer - Applications |
COVID-19-immunoregulation |
Manufacturer - Targets |
Endogenous Metabolite; NF-κB; NO Synthase |
Shipping Temperature |
Room Temperature |
Storage Conditions |
-20°C, 3 years; 4°C, 2 years (Powder) |
Molecular Weight |
202.25 |
Product Description |
SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing. |
Manufacturer - Research Area |
Inflammation/Immunology |
Solubility |
DMSO : 67.5 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic; warming; heat to 60°C) |
Manufacturer - Pathway |
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB |
Isoform |
Human Endogenous Metabolite |
Clinical information |
No Development Reported |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.