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Nicotinamide N-oxide

Nicotinamide N-oxide

Item no.	HY-101407-10mM
Manufacturer	MedChem Express
CASRN	1986-81-8
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL
Category	Neuroscience Neuroinflammation Metabolism Diabetes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.85
Formula	C6H6N2O2
Citations	[1]Real AM, et al. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes. Drug Metab Dispos. 2013 Mar;41(3):550-3. [2]Cutshall NS, et al. Nicotinamide N-oxides as CXCR2 antagonists. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1951-4.
Smiles	O=C(C1=C[N+]([O-])=CC=C1)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1986-81-8
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	CXCR; Drug Metabolite; Endogenous Metabolite; Oxidative Phosphorylation
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	138.126
Product Description	Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor.
Manufacturer - Research Area	Inflammation/Immunology; Endocrinology
Solubility	DMSO : 10 mg/mL (ultrasonic)\|H2O : 20 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease
Isoform	CXCR2
Clinical information	No Development Reported

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HY-101407-10mM-safety-datasheet.pdf