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BI 689648

BI 689648

Item no.	HY-101217-5mg
Manufacturer	MedChem Express
CASRN	1633009-87-6
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 1mg 25 mg 50 mg 5 mg
Category	Metabolism Cholesterol & Lipid Metabolism Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.20
Formula	C16H18N4O2
Citations	[1]Weldon SM, et al. Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates. J Pharmacol Exp Ther. 2016 Oct;359(1):142-50.
Smiles	O=C(N1CCCC2=C1N=CC(C3=CC(COC)=CN=C3)=C2)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1633009-87-6
Available
Product Description	BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	298.34
Clinical Information	No Development Reported
Manufacturers Research Area	Endocrinology
Solubility	DMSO : 30 mg/mL (ultrasonic; warming)
Target	Cytochrome P450
Manufacturers Target	Cytochrome P450
Isoform	CYP11
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-101217-5mg-safety-datasheet.pdf