KI696

Item no.	HY-101140-10mM
Manufacturer	MedChem Express
CASRN	1799974-70-1
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.26
Formula	C28H30N4O6S
Citations	[1]Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59(8):3991-4006.
Smiles	COC1=C(N2C)C(N=N2)=CC([C@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1799974-70-1
Available
Product Description	KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	550.63
Clinical Information	No Development Reported
Manufacturers Research Area	Metabolic Disease; Inflammation/Immunology
Solubility	DMSO : 50 mg/mL (ultrasonic)
Target	Keap1-Nrf2
Manufacturers Target	Keap1-Nrf2
Manufacturers Pathway	NF-κB
Manufacturers Product type	Reference compound

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HY-101140-10mM-safety-datasheet.pdf