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GSK4028

GSK4028

Item no.	HY-101027A-10mM
Manufacturer	MedChem Express
CASRN	2079886-19-2
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.55
Formula	C17H21BrN4O
Citations	[1]Humphreys PG, et al. Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe. J Med Chem. 2017 Jan 26;60(2):695-709.
Smiles	BrC1=C(N[C@H]2C[C@@H](C3=CC=CC=C3)CN(C)C2)C=NN(C)C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2079886-19-2
Available
Product Description	GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	377.28
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Epigenetic Reader Domain; Histone Acetyltransferase
Manufacturers Target	Epigenetic Reader Domain; Histone Acetyltransferase
Isoform	GCN5/PCAF
Manufacturers Pathway	Epigenetics
Manufacturers Product type	Reference compound

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HY-101027A-10mM-safety-datasheet.pdf