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CXCR2-IN-1

CXCR2-IN-1

Item no.	HY-101022-50mg
Manufacturer	MedChem Express
CASRN	1873376-49-8
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Neuroscience Neuroinflammation Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.47
Formula	C19H20Cl2FN3O4S
Citations	[1]Xu H, et al. Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders. ACS Med Chem Lett. 2016 Feb 8;7(4):397-402.
Smiles	ClC1=CC=C(NC(NC2=CC=CC(F)=C2Cl)=O)C(O)=C1S(=O)(C3CCN(C)CC3)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1873376-49-8
Available
Product Description	CXCR2-IN-1 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	476.35
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Endocrinology
Solubility	DMSO : 5.4 mg/mL (ultrasonic; warming)
Target	CXCR
Manufacturers Target	CXCR
Isoform	CXCR2
Manufacturers Pathway	GPCR/G Protein; Immunology/Inflammation
Manufacturers Product type	Reference compound

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HY-101022-50mg-safety-datasheet.pdf