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(1α,1'S,4β)-Lanabecestat

(1α,1'S,4β)-Lanabecestat

Item no.	HY-100740C-2mg
Manufacturer	MedChem Express
CASRN	1384082-96-5
Amount	2mg
Quantity options	100 mg 10mM/1mL 10 mg 2mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	96.01
Citations	[1]Eketjäll S, et al. AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics. J Alzheimers Dis. 2016;50(4):1109-23.
Smiles	NC(C(C)=N1)=N[C@]21C3=C(C=CC(C4=CC(C#CC)=CN=C4)=C3)C[C@]52CC[C@@H](OC)CC5
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(1α,1'S,4β)-AZD3293; (1α,1'S,4β)-LY3314814
Available
Product Description	(1α, 1'S, 4β)-Lanabecestat ((1α, 1'S, 4β)-AZD3293) a less active enantiomer of Lanabecestat. Lanabecestat is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	412.53
Clinical_Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : 250 mg/mL (ultrasonic)
Manufacturers Target	Beta-secretase
Isoform	BACE1
Pathway	Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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