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4E2RCat

4E2RCat

Item no.	HY-100733-10mg
Manufacturer	MedChem Express
CASRN	432499-63-3
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C22H14ClNO4S2
Citations	[1]Cencic R, et al. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85(13):6381-9.
Smiles	O=C(O)C1=CC(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)=CC=C1Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	432499-63-3
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Autophagy; Eukaryotic Initiation Factor (eIF); Virus Protease
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	455.93
Product Description	4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO : 23.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Autophagy; Cell Cycle/DNA Damage
Isoform	eIF4
Clinical information	No Development Reported

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HY-100733-10mg-safety-datasheet.pdf