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Fumarate hydratase-IN-1

Fumarate hydratase-IN-1

Item no.	HY-100004-10mM
Manufacturer	MedChem Express
CASRN	1644060-37-6
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Targets for Rodent Neurosciences By Cell Type Carcinoma Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.93
Formula	C27H30N2O4
Citations	[1]Takeuchi T et al. Identification of Fumarate Hydratase Inhibitors with Nutrient-Dependent Cytotoxicity. J Am Chem Soc, 2015 Jan 21, 137(2): 564-567.
Smiles	O=C(OCC)[C@]1([C@H](CC(NC)=O)C2=O)C(N2CC(C=C3)=CC=C3C4=CC=CC=C4)=CCCC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1644060-37-6
Available
Product Description	Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	446.54
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 50 mg/mL (ultrasonic)
Target	Mitochondrial Metabolism
Manufacturers Target	Mitochondrial Metabolism
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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HY-100004-10mM-safety-datasheet.pdf